Peptides:Chemistry,Biology and Pharmaceutical Sciences（多肽：化学、生物学和药物科学）（全英文会议论文） 115盘 下载 pdf txt 电子版 mobi snb docx

　　The 11th Chinese International Peptide Symposium (CPS-2010),

hosted by Lanzhou University, was held in Lanzhou, China, July 5-8,

2010. More than 300 participants, from 12 countries and districts

as well as represents from 30 or so related companies attended this

symposium. Thus, it was gratifying to see that this meeting

retained both its international flavor and participants loyalty at

a time when there are a great many symposia held each year on

similar subjects. The goal of this symposium was to provide a forum

for exchange of ideas, review of the progress in the field of

peptide research, encourage the cooperation between the

international and Chinese scientific communities. We believe that

this goal had been achieved.

The scientific program, thanks to the insights and efforts of the

program committee, was extraordinary rich, diverse and exciting. It

was comprised of 14 sessions with 22 plenary lectures, 37 invited

lectures and 116 poster presentations, concerning bioactive

peptides, peptide immunology, structure and conformation of

peptides and proteins, molecular diversity and peptide libraries,

synthetic methods, de novo design and synthesis of proteins and

peptides, ligand-receptor interactions, the

chemistry-biology-interface, self-assembling peptides and

challenging problems in peptides.

Dr. John D. Wade and Dr. Yanmei Li were the recipients of ‘Cathay

Award’ sponsored by H. H. Liu Education Foundation, offering their

seminal contributions to peptide science and the Chinese

International Peptide Symposium. Dr. Saburo Aimoto and Dr. Luhua

Lai were the recipients of ‘Xiaoyu Hu Memorial Award’ sponsored by

Hainan Zhonghe (Group) Co. Ltd, offering their great contributions

in peptide science, peptide application and Chinese International

Peptide Symposium. Especially, it should be mentioned that ‘Xiaoyu

Hu Memorial Award’ was first set up at the 11th CPS to commemorate

Professor Xiaoyu Hu for his great contribution to the development

of peptide science and peptide application in China. Four young

outstanding scientists were selected by the International Program

Committee to receive the Young Peptide Scientist Award , which was

sponsored by Hainan Zhonghe (Group) Co. Ltd.

The enthusiastic cooperation and prominent contributions were

gratifying and the active response of the invited speakers

contributed to the success of the symposium. The presentations were

of excellent caliber and represented the most current and

significant aspects of peptide science.

I would like to acknowledge academicians of chinese academy of

sciences, Professor Youshang Zhang and Professor Yundong Wu for

their kindness in supporting and serving as the chairman of the

awarding committee for the ‘Cathay Award’ and ‘Xiaoyu Hu Memorial

Award’ respectively. The success of the 11th CPS was largely due to

the dedication, enthusiasm and hard work of the local organizing

committee, who for the most part consisted of volunteers. As

Symposium Chair, I am appreciated for their contributions very

much.

Preface Ⅴ

The Eleventh Chinese Peptide Symposium (CPS-2010) Ⅶ

Acknowledgments Ⅹ

Cathay Award Ⅺ

Xiaoyu Hu Memorial Award Ⅻ

Chinese Peptide Symposium ⅩⅢ

Abbreviations ⅩⅣPreface

The Eleventh Chinese Peptide Symposium (CPS-2010)

Acknowledgments

Cathay Award

Xiaoyu Hu Memorial Award

Chinese Peptide Symposium

Abbreviations

Session 1 Design of Peptides and Mimetics 1

Biomimetic Nanostructures Based on Enforced Folding and Assembly

3

Bing Gong

Agonist vs. Antagonist Behavior of Opioid Peptides Containing

Novel

Tyrosine or Phenylalanine Analogues in Place of Tyr1 13

Grazyna Weltrowska, Irena Berezowska, Brian C. Wilkes, Carole

Lemieux,

Nga N. Chung, Jinguo Ding, Yixin Lu, Peter W. Schiller,

Novel Non-Peptide Ghrelin Receptor Ligands Based on

3,4,5-Trisubstituted 1,2,4-Triazoles 20

Jean-Alain Fehrentz, Anne-Laure Blayo, Mathieu Bibian, Aline

Moulin, Luc

Demange, Damien Boeglin, Céline M’Kadmi, Jean-Claude

Galleyrand,

Didier Gagne, Vittorio Locatelli, Antonello Torsello, Daniel

Perrissoud,

Jean Martinez,

Synthesis and Structure-Activity Relationship of

Marinostatin,

An Ester-Linked Serine Protease Inhibitor 25

Misako Taichi, Toshimasa Yamazaki, Tadashi Teshima, Yuji

Nishiuchi

Mitocryptides: A Novel Family of Neutrophil-Activating Peptides

Derived

from Mitochondrial Proteins and Their Regulatory Mechanisms

30

Hidehito Mukai, Tetsuo Seki, Akiyoshi Fukamizu, Yoshiaki Kiso

Novel Opioid Peptide Derived Antagonists Containing 3-(2,6-

Dimethyl-4-

Carbamoylphenyl)-Propanoic Acid (Dcp) in Place of Tyr1 33

Peter W. Schiller, Grazyna Weltrowska, Thi M.-D. Nguyen, Carole

Lemieux,

Nga N. Chung, Tze Keong Lum, Yoon Wui Leow Augustine, Yixin

Lu

Design, Synthesis and Evaluation of Antitumor Activity

against

Human Cancer Cell Lines, Sansalvamide Analogues 39

Xiaoli Zhen, Yihua Yang, Junzhang Li, Xia Tian, Hua Zhang, Shouxin

Liu

Session 2 Peptide Synthesis and Preparation 41

Regioselective Disulfide Bond Formation during SPS of Human

Relaxin-3:

Evaluation of An Alternative Method for Removal of the S-Acm Groups

via

Reaction with Silver Triflate and Subsequent Mild Aqueous

DMSO Oxidation 43

Feng Lin, John D. Wade

Synthetic Studies of Membrane Proteins: Subunit C of Human

F1Fo-ATP

Synthase and Voltage Sensor Only Protein (78-222) 47

Saburo Aimoto, Ken’ichiro Nakamura, Takeshi Sato, Toru

Kawakami,

Toshiaki Hara

One-Pot Synthesis of Rigid Cyclic N-Methyl-γ-Peptides 54

Zhongzhu Chen, Liangchun Li, Menglan Lv, Jin Zhu and Jingen

Deng

Tbfmoc Methioine: Its Synthesis and Application for the Solid

Phase

Synthesis of Ubiquitin Analogues and Product Purification 58

Naifeng Hu, Zhi Jin, Pu Wang

Intein-Mediated Biosynthesis of Bracelet Cyclotide 63

Xinya Hemu, Lin Cai, Clarence T. T. , James P. Tam

Convergent and Atom-Economic Synthesis of Phosphinopeptides

67

Fanhua Meng, Jiaxi Xu

One-Step Oxidative Folding of A Novel Cystine-Knot Cyclotide

Under Denaturation Conditions 69

Clarence T. T. , Misako Taichi, Hideki Nishio, Yuji

Nishiuchi,

James P. Tam

Synthesis of Angiotensin I-Converting Enzyme Inhibitory Peptides

and

Their Self-Assembling Microstructure Characterization 72

Dawei Li, Yan Ding, Gang Cao, Ruijie Zhang, Jin Ren, Chuanguang

Qin

Fast Automated Synthesis of An Antimicrobial Peptide Analog

Using UV-Monitoring on the Tribute? 77

German E. Fuentes, Christina A. Chantell, Hirendra Patel,

Mahendra

Menakuru

Synthesis of Cyclic Peptides by Alknye-Azide Click Chemistry

Cyclization 81

Liangyou Wang, Dongdong Lu, Mingxing Lu

Thioester Preparation through O-S Acyl Shift under Acidic Condition

83

Khee Dong Eom, Young Soon Shin, James P. Tam

A Novel Strategy for Total Solid-Phase Synthesis of

Kahalalide A Derivatives 86

Tingting Wei, Jin Ren, Xiaoya Shang, Gang Cao, Chuanguang Qin

Session 3 Methodologies in Peptide Research 91

Protein Synthesis Using Novel Ligation Partners 93

Wen Hou, Renliang Yang, Fupeng Li, Xiaohong Zhang, Chuanfa

Liu

Expanding Role of Mass Spectrometry for Characterization of

Proteins 97

Pui-kin So, Zhongping Yao

Effect of pH on the Self-Assembly of Surfactant-Like Peptides

102

Shuyi Han, Jing Wang, Hai Xu

Conformational Isomers in N-Methylzygosporamide Cyclic

Pentapeptides 110

Yihua Yang, Shirui Gao, Xianrui Yuan, Shouxin Liu, Wei Meng, Guodi

Qi

Interaction between Amyloid-β-Peptide (1-40) and Its

Aggregation

Inhibitors Studied by Circular Dichroism 112

Qing Zeng

Disulfide Bond Formation Directed by Watson-Crick Base Pairing

116

Fupeng Li, Xiaohong Zhang, Wen Hou, Chuanfa Liu

Interfacial Adsorption of Novel Lipopeptide Surfactant C14K3: A

Combined

Study of Spectroscopic Ellipsometry and Neutron Reflection

120

Donghui Jia, Kai Tao, Jiqian Wang, Xiubo Zhao, Hai Xu, John R.

P.

Webster, Jian R. Lu

Session 4 Peptide Therapeutics and Application 135

Peptide-Based Nanoparticles for Cancer Therapy and Imaging

137

Yuanpei Li, Kai Xiao, Juntao Luo, Wenwu Xiao, Joyce Lee,

Lorenzo Berti, Kit S. Lam

Involvement of Na+,K+-ATPase in Leukemia Cell Apoptosis

by Modulating Sensitivity 145

Wu Yin, Wei Cheng, Wei Chen, Dan Cao, Su Feng, Xinyin Chen, Jin

Zhao,

Yilin Shi, Zichun Hua

Short Constrained Dipeptide Mimic Oligomers as Uncharged Cell

Penetrating Compounds 157

Lubomir L. Vezenkov, Christophe André, David Paramelle, Marie

Maynadier,

Jean-Francois Hernandez, Marcel Garcia, Monique Calmès, Gilles

Subra,

Ettore Benedetti, Jean Martinez, Muriel Amblard

Synthesis and Biological Properties of Peptide-siRNA Conjugates

161

Zhenjun Yang, Xiaofeng Wang, Yang Liu, Yue Chen, Feilin Nie, Lihe

Zhang

FGF-P Facilitates Cell Proliferation Following Ionizing Radiation

167

Yeping Tian, Shanmin Yang, Mei Zhang, Yongbing Cao, Bingrong

Zhang,

Lei Zhang, Liangjie Yin, Kunzhong Zhang, Steven G. Stwarts, Bruce

M.

Fentona, Paul Okunieff, Lurong Zhang

Synthesis, Evaluation and Molecular Modeling Study of

L-2-amino-7/8-

Bromoalkanoic Acid Derivatives as Histone Deacetylase Inhibitors

172

Dawei Huang, Xiaohui Li , Zhilong Xiu, Norikazu Nishino

Thirteen-Membered Cyclic Tetrapeptides as Histone Deacetylase

Inhibitors 177

Hongfang Chi, Yasuhiko Otsuka, Tamaki Kato, Norikazu Nishino,

Akihiro Ito, Minoru Yoshida

Antimicrobial Peptide May be Desirable Candidate for the Treatment

of

Multidrug-Resistant Cancer & Bacteria: A Simple Introduction to

the

Therapeutic Effects of A Novel Antimicrobial Peptide Polybia-MPI

182

Kairong Wang, Bangzhi Zhang, Jiexi Yan, Wei Zhang, Ru Chen,

Jingjing Song, Rui Wang

Remodeling of Cyclic Tetrapeptides Framework of Chlamydocin

as

Histone Deacetylase Inhibitors 188

Jiani Li, Xiaohui Li, Yasuhiko Otsuka, Tamaki Kato, Norikazu

Nishino,

Akihiro Ito, Minoru Yoshida

Identification of Novel HLA-A*0201-Restricted Cytotoxic T

lymphocyte Epitopes from PLAC1 in Breast Cancer 192

Wei Liu, Mingxia Zhai, Chao Dai, Yuanming Qi, Yanfeng Gao

Session 5 Bioactive Peptides and Pharmacology 197

In Vitro Characterization for the Effects of Insect Kinins on

Mouse

Distal Colonic Motility 199

Longfei Yang, Yang Xiao, Yun Huang, Guoning Ma, Zhiyuan Cong,

Shouliang Dong

Evaluation of the Bioequivalence of the 20 mg /10 ml Doses of

Two

Injectable Preparations of Eptifibatide: A Randomized,

Open-Label,

Two-Period Crossover Study in Healthy Adult Male Chinese Volunteers

204

Yanhui Gao, Baoqiu Li, Jun Sun

The Characteristics of Sleep-Wake States and Potential

Neuronal

Targets for Neuropeptide S 210

Peng Zhao, Yufeng Shao, Min Zhang, Kun Fan, Rui Wang, Yiping

Hou

Antibacterial Activity of Surfactant-Like Linear Amphipathic

Cationic Peptides 218

Jing Hu, Cui X. Chen, Sheng Z. Zhang, Hai Xu, Jian R. Lu

Comparison of the Pharmacological Functions of the NPFF1

and NPFF2 Receptors Ligands 229

Quan Fang, Ning Li, Rui Wang

Preparation of Monomeric B27 Lys Destripeptide Insulin by

Intein Mediated Expression in E. Coli 236

Lujuan Li, Helong Hao, Yuanhao Qiao, Ting Chen

Endomorphins Prevent Cardiac Oxidative Damage Induced

by Cadmium Chloride in Rats 241

Pin Gong, Fuxin Chen, Rui Wang

Study on Anticancer Mechanism of Cyclic Tetrapeptide HDACIs

246

Shimiao Wang, Xiaohui Li, Zhilong Xiu, Norikazu Nishino 246

Biological Roles of Hemokinin-1: A Novel Member of

the Tachykinin Family 251

Ziqing Kong, Wenle Yang, Caiyun Fu, Youli Zhao, Yan Tao, Rui

Wang

Author Index 257

Subject Index 260

Session 1 Design of Peptides and Mimetics

Biomimetic Nanostructures Based on Enforced Folding and

Assembly

Bing Gong

Agonist vs. Antagonist Behavior of Opioid Peptides Containing

Novel

Tyrosine or Phenylalanine Analogues in Place of Tyr1

Grazyna Weltrowska, Irena Berezowska, Brian C. Wilkes, Carole

Lemieux,

Nga N. Chung, Jinguo Ding, Yixin Lu, Peter W. Schiller,

Novel Non-Peptide Ghrelin Receptor Ligands Based on

3,4,5-Trisubstituted 1,2,4-Triazoles

Jean-Alain Fehrentz, Anne-Laure Blayo, Mathieu Bibian, Aline

Moulin, Luc

Demange, Damien Boeglin, Céline M’Kadmi, Jean-Claude

Galleyrand,

Didier Gagne, Vittorio Locatelli, Antonello Torsello, Daniel

Perrissoud,

Jean Martinez,

Synthesis and Structure-Activity Relationship of

Marinostatin,

An Ester-Linked Serine Protease Inhibitor

Misako Taichi, Toshimasa Yamazaki, Tadashi Teshima, Yuji

Nishiuchi

Mitocryptides: A Novel Family of Neutrophil-Activating Peptides

Derived

from Mitochondrial Proteins and Their Regulatory Mechanisms

Hidehito Mukai, Tetsuo Seki, Akiyoshi Fukamizu, Yoshiaki Kiso

Novel Opioid Peptide Derived Antagonists Containing 3-(2,6-

Dimethyl-4-

Carbamoylphenyl)-Propanoic Acid (Dcp) in Place of Tyr1

Peter W. Schiller, Grazyna Weltrowska, Thi M.-D. Nguyen, Carole

Lemieux,

Nga N. Chung, Tze Keong Lum, Yoon Wui Leow Augustine, Yixin

Lu

Design, Synthesis and Evaluation of Antitumor Activity

against

Human Cancer Cell Lines, Sansalvamide Analogues

Xiaoli Zhen, Yihua Yang, Junzhang Li, Xia Tian, Hua Zhang, Shouxin

Liu

Session 2 Peptide Synthesis and Preparation

Regioselective Disulfide Bond Formation during SPS of Human

Relaxin-3:

Evaluation of An Alternative Method for Removal of the S-Acm Groups

via

Reaction with Silver Triflate and Subsequent Mild Aqueous

DMSO Oxidation

Feng Lin, John D. Wade

Synthetic Studies of Membrane Proteins: Subunit C of Human

F1Fo-ATP

Synthase and Voltage Sensor Only Protein (78-222)

Saburo Aimoto, Ken’ichiro Nakamura, Takeshi Sato, Toru

Kawakami,

Toshiaki Hara

One-Pot Synthesis of Rigid Cyclic N-Methyl-γ-Peptides

Zhongzhu Chen, Liangchun Li, Menglan Lv, Jin Zhu and Jingen

Deng

Tbfmoc Methioine: Its Synthesis and Application for the Solid

Phase

Synthesis of Ubiquitin Analogues and Product Purification

Naifeng Hu, Zhi Jin, Pu Wang

Intein-Mediated Biosynthesis of Bracelet Cyclotide

Xinya Hemu, Lin Cai, Clarence T. T. , James P. Tam

Convergent and Atom-Economic Synthesis of Phosphinopeptides

Fanhua Meng, Jiaxi Xu

One-Step Oxidative Folding of A Novel Cystine-Knot Cyclotide

Under Denaturation Conditions

Clarence T. T. , Misako Taichi, Hideki Nishio, Yuji

Nishiuchi,

James P. Tam

Synthesis of Angiotensin I-Converting Enzyme Inhibitory Peptides

and

Their Self-Assembling Microstructure Characterization

Dawei Li, Yan Ding, Gang Cao, Ruijie Zhang, Jin Ren, Chuanguang

Qin

Fast Automated Synthesis of An Antimicrobial Peptide Analog

Using UV-Monitoring on the Tribute?

German E. Fuentes, Christina A. Chantell, Hirendra Patel,

Mahendra

Menakuru

Synthesis of Cyclic Peptides by Alknye-Azide Click Chemistry

Cyclization

Liangyou Wang, Dongdong Lu, Mingxing Lu

Thioester Preparation through O-S Acyl Shift under Acidic

Condition

Khee Dong Eom, Young Soon Shin, James P. Tam

A Novel Strategy for Total Solid-Phase Synthesis of

Kahalalide A Derivatives

Tingting Wei, Jin Ren, Xiaoya Shang, Gang Cao, Chuanguang Qin

Session 3 Methodologies in Peptide Research

Protein Synthesis Using Novel Ligation Partners

Wen Hou, Renliang Yang, Fupeng Li, Xiaohong Zhang, Chuanfa

Liu

Expanding Role of Mass Spectrometry for Characterization of

Proteins

Pui-kin So, Zhongping Yao

Effect of pH on the Self-Assembly of Surfactant-Like Peptides

Shuyi Han, Jing Wang, Hai Xu

Conformational Isomers in N-Methylzygosporamide Cyclic

Pentapeptides

Yihua Yang, Shirui Gao, Xianrui Yuan, Shouxin Liu, Wei Meng, Guodi

Qi

Interaction between Amyloid-β-Peptide (1-40) and Its

Aggregation

Inhibitors Studied by Circular Dichroism

Qing Zeng

Disulfide Bond Formation Directed by Watson-Crick Base

Pairing

Fupeng Li, Xiaohong Zhang, Wen Hou, Chuanfa Liu

Interfacial Adsorption of Novel Lipopeptide Surfactant C14K3: A

Combined

Study of Spectroscopic Ellipsometry and Neutron Reflection

Donghui Jia, Kai Tao, Jiqian Wang, Xiubo Zhao, Hai Xu, John R.

P.

Webster, Jian R. Lu

Session 4 Peptide Therapeutics and Application

Peptide-Based Nanoparticles for Cancer Therapy and Imaging

Yuanpei Li, Kai Xiao, Juntao Luo, Wenwu Xiao, Joyce Lee,

Lorenzo Berti, Kit S. Lam

Involvement of Na+,K+-ATPase in Leukemia Cell Apoptosis

by Modulating Sensitivity

Wu Yin, Wei Cheng, Wei Chen, Dan Cao, Su Feng, Xinyin Chen, Jin

Zhao,

Yilin Shi, Zichun Hua

Short Constrained Dipeptide Mimic Oligomers as Uncharged Cell

Penetrating Compounds

Lubomir L. Vezenkov, Christophe André, David Paramelle, Marie

Maynadier,

Jean-Francois Hernandez, Marcel Garcia, Monique Calmès, Gilles

Subra,

Ettore Benedetti, Jean Martinez, Muriel Amblard

Synthesis and Biological Properties of Peptide-siRNA

Conjugates

Zhenjun Yang, Xiaofeng Wang, Yang Liu, Yue Chen, Feilin Nie, Lihe

Zhang

FGF-P Facilitates Cell Proliferation Following Ionizing

Radiation

Yeping Tian, Shanmin Yang, Mei Zhang, Yongbing Cao, Bingrong

Zhang,

Lei Zhang, Liangjie Yin, Kunzhong Zhang, Steven G. Stwarts, Bruce

M.

Fentona, Paul Okunieff, Lurong Zhang

Synthesis, Evaluation and Molecular Modeling Study of

L-2-amino-7/8-

Bromoalkanoic Acid Derivatives as Histone Deacetylase

Inhibitors

Dawei Huang, Xiaohui Li , Zhilong Xiu, Norikazu Nishino

Thirteen-Membered Cyclic Tetrapeptides as Histone Deacetylase

Inhibitors

Hongfang Chi, Yasuhiko Otsuka, Tamaki Kato, Norikazu Nishino,

Akihiro Ito, Minoru Yoshida

Antimicrobial Peptide May be Desirable Candidate for the Treatment

of

Multidrug-Resistant Cancer & Bacteria: A Simple Introduction to

the

Therapeutic Effects of A Novel Antimicrobial Peptide

Polybia-MPI

Kairong Wang, Bangzhi Zhang, Jiexi Yan, Wei Zhang, Ru Chen,

Jingjing Song, Rui Wang

Remodeling of Cyclic Tetrapeptides Framework of Chlamydocin

as

Histone Deacetylase Inhibitors

Jiani Li, Xiaohui Li, Yasuhiko Otsuka, Tamaki Kato, Norikazu

Nishino,

Akihiro Ito, Minoru Yoshida

Identification of Novel HLA-A*0201-Restricted Cytotoxic T

lymphocyte Epitopes from PLAC1 in Breast Cancer

Wei Liu, Mingxia Zhai, Chao Dai, Yuanming Qi, Yanfeng Gao

Session 5 Bioactive Peptides and Pharmacology

In Vitro Characterization for the Effects of Insect Kinins on

Mouse

Distal Colonic Motility

Longfei Yang, Yang Xiao, Yun Huang, Guoning Ma, Zhiyuan Cong,

Shouliang Dong

Evaluation of the Bioequivalence of the 20 mg /10 ml Doses of

Two

Injectable Preparations of Eptifibatide: A Randomized,

Open-Label,

Two-Period Crossover Study in Healthy Adult Male Chinese

Volunteers

Yanhui Gao, Baoqiu Li, Jun Sun

The Characteristics of Sleep-Wake States and Potential

Neuronal

Targets for Neuropeptide S

Peng Zhao, Yufeng Shao, Min Zhang, Kun Fan, Rui Wang, Yiping

Hou

Antibacterial Activity of Surfactant-Like Linear Amphipathic

Cationic Peptides

Jing Hu, Cui X. Chen, Sheng Z. Zhang, Hai Xu, Jian R. Lu

Comparison of the Pharmacological Functions of the NPFF

and NPFF2 Receptors Ligands

Quan Fang, Ning Li, Rui Wang

Preparation of Monomeric B27 Lys Destripeptide Insulin by

Intein Mediated Expression in E. Coli

Lujuan Li, Helong Hao, Yuanhao Qiao, Ting Chen

Endomorphins Prevent Cardiac Oxidative Damage Induced

by Cadmium Chloride in Rats

Pin Gong, Fuxin Chen, Rui Wang

Study on Anticancer Mechanism of Cyclic Tetrapeptide HDACIs

Shimiao Wang, Xiaohui Li, Zhilong Xiu, Norikazu Nishino

Biological Roles of Hemokinin-1: A Novel Member of

the Tachykinin Family

Ziqing Kong, Wenle Yang, Caiyun Fu, Youli Zhao, Yan Tao, Rui

Wang

Author Index

Subject Index

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前言

The 11th Chinese International Peptide Symposium (CPS-2010),

hosted by Lanzhou University, was held in Lanzhou, China, July 5-8,

2010. More than 300 participants, from 12 countries and districts

as well as represents from 30 or so related companies attended this

symposium. Thus, it was gratifying to see that this meeting

retained both its international flavor and participants loyalty at

a time when there are a great many symposia held each year on

similar subjects. The goal of this symposium was to provide a forum

for exchange of ideas, review of the progress in the field of

peptide research, encourage the cooperation between the

international and Chinese scientific communities. We believe that

this goal had been achieved. 

    The scientific program, thanks to the insights

and efforts of the program committee, was extraordinary rich,

diverse and exciting. It was comprised of 14 sessions with 22

plenary lectures, 37 invited lectures and 116 poster presentations,

concerning bioactive peptides, peptide immunology, structure and

conformation of peptides and proteins, molecular diversity and

peptide libraries, synthetic methods, de novo design and synthesis

of proteins and peptides, ligand-receptor interactions, the

chemistry-biology-interface, self-assembling peptides and

challenging problems in peptides.  

书籍介绍

《多肽、化学、生物和药物科学》内容简介：The 11th Chinese International Peptide Symposium (CPS-2010), hosted by Lanzhou University, was held in Lanzhou, China, July 5-8, 2010. More than 300 participants, from 12 countries and districts as well as represents from 30 or so related companies attended this symposium. Thus, it was gratifying to see that this meeting retained both its international flavor and participants loyalty at a time when there are a great many symposia held each year on similar subjects. The goal of this symposium was to provide a forum for exchange of ideas, review of the progress in the field of peptide research, encourage the cooperation between the international and Chinese scientific communities. We believe that this goal had been achieved.

The scientific program, thanks to the insights and efforts of the program committee, was extraordinary rich, diverse and exciting. It was comprised of 14 sessions with 22 plenary lectures, 37 invited lectures and 116 poster presentations, concerning bioactive peptides, peptide immunology, structure and conformation of peptides and proteins, molecular diversity and peptide libraries, synthetic methods, de novo design and synthesis of proteins and peptides, ligand-receptor interactions, the chemistry-biology-interface, self-assembling peptides and challenging problems in peptides.