Apoptosis（ISBN=9780521626798） 英文原版 115盘 下载 pdf txt 电子版 mobi snb docx

　　The concept of programmed cell death, or apoptosis, has

exploded into a major scientific field of interest for cell

biologists, oncologists, and many other biomedical researchers.

Apoptosis occurs throughout the lifetime of most multicellular

organisms. During development, for example, the selective death of

cells is vital to remove tissue between the digits to produce

fingers and toes. Apoptosis is also necessary to destroy cells that

represent a threat to the integrity of the organism, for example

cells infected by a virus. In many cancers the genes regulating

apoptosis are defective, producing immortal, continuously

proliferating cells. This book discusses the philosophical and

technical difficulties in defining the moment of death for a cell,

as well as the biological implications and significance of

programmed cell death. Recent developments in the genetic control

and interacting gene networks associated with apoptosis are

presented. The book is written for advanced undergraduate and

postgraduate students, and is highly illustrated to aid

understanding.

1. Dead or alive

2. How to die

3. What to wear and who clears up the rubbish

4. To reproduce or die

5. The judge, jury, and executioner - the genes that control cell

death

6. Stem cells

7. An in vivo system to study apoptosis: the small intestine

8. Cell death in diverse systems

9. Measuring levels of cell death

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媒体评论

　　'A compelling read for anyone interested in organismal

development ... This is a timely publication and one that will fill

a much-needed niche on biologist's bookshelves.' Biologist

书籍介绍

This book describes the biological implications and significance of apoptosis. Occurring naturally throughout the lifetime of most multicellular organisms, apoptosis, or programmed cell death, accounts for the continuous turnover of cells in the body. However, the genes regulating apoptosis are defective in many cancers.